› 3uyn

X-ray diffraction
2.6Å resolution

Function and Biology Details

Reaction catalysed: 
H(2)CO(3) = CO(2) + H(2)O
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139595 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Carbonic anhydrase 3 Chain: A
Molecule details ›
Chain: A
Length: 260 amino acids
Theoretical weight: 29.56 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P07451 (Residues: 1-260; Coverage: 100%)
Gene name: CA3
Sequence domains: Eukaryotic-type carbonic anhydrase
Structure domains: Alpha carbonic anhydrase

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P212121
Unit cell:
a: 80.198Å b: 78.066Å c: 43.383Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.206 0.206 0.201
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Structural annotation of human carbonic anhydrases.
Aggarwal et al. (2013)
3 more

1 mention without citation

Improved serological detection of rheumatoid arthritis: a highly antigenic mimotope of carbonic anhydrase III selected in a murine model by phage display.
Araujo et al. (2015)