Function and Biology Details
Reaction catalysed:
Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assemblies composition:
Assembly name:
Histone deacetylase 4 and 14-3-3 protein gamma (preferred)
PDBe Complex ID:
PDB-CPX-157480 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
14-3-3 protein gamma
Molecule details ›
Chain: A
Length: 248 amino acids
Theoretical weight: 28.42 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: 14-3-3 protein
Structure domains: 14-3-3 domain
Length: 248 amino acids
Theoretical weight: 28.42 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P61981 (Residues: 1-247; Coverage: 100%)
Sequence domains: 14-3-3 protein
Structure domains: 14-3-3 domain
Histone deacetylase 4
Molecule details ›
Chain: B
Length: 17 amino acids
Theoretical weight: 1.88 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Length: 17 amino acids
Theoretical weight: 1.88 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: P56524 (Residues: 343-359; Coverage: 2%)
