Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138518 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Interleukin-5
Molecule details ›
Chains: A, B
Length: 119 amino acids
Theoretical weight: 13.37 KDa
Source organism: Homo sapiens
Expression system: CELL-FREE SYNTHESIS
UniProt:
Sequence domains: Interleukin 5
Structure domains: Growth Hormone; Chain: A;
Length: 119 amino acids
Theoretical weight: 13.37 KDa
Source organism: Homo sapiens
Expression system: CELL-FREE SYNTHESIS
UniProt:
- Canonical:
P05113 (Residues: 23-134; Coverage: 97%)
Sequence domains: Interleukin 5
Structure domains: Growth Hormone; Chain: A;
Interleukin-5 receptor subunit alpha
Molecule details ›
Chain: C
Length: 322 amino acids
Theoretical weight: 36.39 KDa
Source organism: Homo sapiens
Expression system: CELL-FREE SYNTHESIS
UniProt:
Sequence domains: Interleukin-6 receptor alpha chain, binding
Structure domains: Immunoglobulins
Length: 322 amino acids
Theoretical weight: 36.39 KDa
Source organism: Homo sapiens
Expression system: CELL-FREE SYNTHESIS
UniProt:
- Canonical: Q01344 (Residues: 21-335; Coverage: 79%)
Sequence domains: Interleukin-6 receptor alpha chain, binding
Structure domains: Immunoglobulins
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SPRING-8 BEAMLINE BL41XU
Spacegroup:
P212121
Expression system: CELL-FREE SYNTHESIS
