› 3vwx

X-ray diffraction
1.8Å resolution

Structural analysis of an epsilon-class glutathione S-transferase from housefly, Musca domestica

Released:
DOI: 10.2210/pdb3vwx/pdb
PDB entry 3vwx coloured by chain, front view.
PDB entry 3vwx coloured by chain, side view.
PDB entry 3vwx coloured by chain, top view.
Source organism: Musca domestica
Primary publication:
Structural analysis of an epsilon-class glutathione transferase from housefly, Musca domestica.
Nakamura C, Yajima S, Miyamoto T, Sue M
Biochem Biophys Res Commun 430 1206-11 (2013)
PMID: 23268341

Function and Biology Details

Reaction catalysed: 
RX + glutathione = HX + R-S-glutathione
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193626 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutathione s-transferase 6B Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 222 amino acids
Theoretical weight: 25.03 KDa
Source organism: Musca domestica
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9U795 (Residues: 1-222; Coverage: 100%)
Gene name: GST-6B
Sequence domains:
Structure domains:

Ligands and Environments


Cofactor: Ligand GSH 4 x GSH
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-5A
Spacegroup: P31
Unit cell:
a: 87.548Å b: 87.548Å c: 131.883Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.165 0.164 0.191
Expression system: Escherichia coli

Quick links

Citations

3 citation in other articles

The transcriptome response of Heliconius melpomene larvae to a novel host plant.
Yu et al. (2016)
2 more

2 mentions without citation

Comparison of epsilon- and delta-class glutathione S-transferases: the crystal structures of the glutathione S-transferases DmGSTE6 and DmGSTE7 from Drosophila melanogaster.
Scian et al. (2015)
1 more