› 3vze

X-ray diffraction
1.9Å resolution

Crystal structure of human pancreatic secretory protein ZG16p with alpha1,3-mannobiose

Released:
DOI: 10.2210/pdb3vze/pdb
PDB entry 3vze coloured by chain, front view.
PDB entry 3vze coloured by chain, side view.
PDB entry 3vze coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural basis for multiple sugar recognition of Jacalin-related human ZG16p lectin.
Kanagawa M, Liu Y, Hanashima S, Ikeda A, Chai W, Nakano Y, Kojima-Aikawa K, Feizi T, Yamaguchi Y
J Biol Chem 289 16954-65 (2014)
PMID: 24790092

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-130101 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Zymogen granule membrane protein 16 Chain: A
Molecule details ›
Chain: A
Length: 141 amino acids
Theoretical weight: 15.5 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O60844 (Residues: 21-159; Coverage: 92%)
Gene name: ZG16
Sequence domains: Jacalin-like lectin domain
Structure domains: Jacalin-like lectin domain

Ligands and Environments

Carbohydrate polymer : NEW Components: MAN
Carbohydrate polymer
1 bound ligand:
Ligand CL 2 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE AR-NW12A
Spacegroup: P21212
Unit cell:
a: 58.32Å b: 73.195Å c: 30.501Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.186 0.183 0.234
Expression system: Escherichia coli

Quick links

Citations

7 review citations

Lectin domains at the frontiers of plant defense.
Lannoo et al. (2014)
6 more

2 mentions without citation

Structural basis for multiple sugar recognition of Jacalin-related human ZG16p lectin.
Kanagawa et al. (2014)
1 more