Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
Non-homologous end-joining factor 1 (preferred)
PDBe Complex ID:
PDB-CPX-190703 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Non-homologous end-joining factor 1
Molecule details ›
Chains: A, B
Length: 235 amino acids
Theoretical weight: 26.64 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: XLF-Cernunnos, XRcc4-like factor, NHEJ component
Length: 235 amino acids
Theoretical weight: 26.64 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q9H9Q4 (Residues: 1-233; Coverage: 78%)
Sequence domains: XLF-Cernunnos, XRcc4-like factor, NHEJ component
DNA repair protein XRCC4
Molecule details ›
Chains: C, D
Length: 184 amino acids
Theoretical weight: 21.06 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: DNA double-strand break repair and V(D)J recombination protein XRCC4
Length: 184 amino acids
Theoretical weight: 21.06 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: Q13426 (Residues: 1-164; Coverage: 49%)
Sequence domains: DNA double-strand break repair and V(D)J recombination protein XRCC4
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
DIAMOND BEAMLINE I03
Spacegroup:
P65
Expression system: Escherichia coli
