Function and Biology Details
Reaction catalysed:
(1a) 2 farnesyl diphosphate = diphosphate + presqualene diphosphate
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- Squalene/phytoene synthase, conserved site
- Isoprenoid synthase domain superfamily
- Squalene/phytoene synthase
- Trans-isoprenyl diphosphate synthases, head-to-head
- Squalene synthase-like
- Trans-isoprenyl diphosphate synthases, eukaryotic-type
- Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Squalene synthase (preferred)
PDBe Complex ID:
PDB-CPX-175452 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Squalene synthase
Molecule details ›
Chains: A, B, C, D
Length: 365 amino acids
Theoretical weight: 41.86 KDa
Source organism: Trypanosoma cruzi strain CL Brener
Expression system: Escherichia coli
UniProt:
Sequence domains: Squalene/phytoene synthase
Structure domains: Farnesyl Diphosphate Synthase
Length: 365 amino acids
Theoretical weight: 41.86 KDa
Source organism: Trypanosoma cruzi strain CL Brener
Expression system: Escherichia coli
UniProt:
- Canonical:
Q4CWB4 (Residues: 25-368; Coverage: 85%)
Sequence domains: Squalene/phytoene synthase
Structure domains: Farnesyl Diphosphate Synthase
