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Crystal structure of BCL-XL in complex with inhibitor (WEHI-539)

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: regulation of apoptotic process
Cellular component: not assigned

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GO terms

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF00452
Domain description: Apoptosis regulator proteins, Bcl-2 family
Occurring in:
  1. Bcl-2-like protein 1
The deposited structure of PDB entry 3zlr contains 2 copies of Pfam domain PF00452 (Apoptosis regulator proteins, Bcl-2 family) in Bcl-2-like protein 1. Showing 1 copy in chain A.

PF02180
Domain description: Bcl-2 homology region 4
Occurring in:
  1. Bcl-2-like protein 1
The deposited structure of PDB entry 3zlr contains 2 copies of Pfam domain PF02180 (Bcl-2 homology region 4) in Bcl-2-like protein 1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR026298
Domain description: Bcl-2 family
Occurring in:
  1. Bcl-2-like protein 1
IPR003093
Domain description: Apoptosis regulator, Bcl-2 protein, BH4
Occurring in:
  1. Bcl-2-like protein 1
IPR013279
Domain description: Apoptosis regulator, Bcl-X
Occurring in:
  1. Bcl-2-like protein 1
IPR036834
Domain description: Bcl-2-like superfamily
Occurring in:
  1. Bcl-2-like protein 1
IPR020726
Domain description: Apoptosis regulator, Bcl-2, BH2 motif, conserved site
Occurring in:
  1. Bcl-2-like protein 1
IPR020717
Domain description: Apoptosis regulator, Bcl-2, BH1 motif, conserved site
Occurring in:
  1. Bcl-2-like protein 1
IPR046371
Domain description: Bcl-2, Bcl-2 homology region 1-3
Occurring in:
  1. Bcl-2-like protein 1
IPR002475
Domain description: Bcl2-like
Occurring in:
  1. Bcl-2-like protein 1
IPR020728
Domain description: Apoptosis regulator, Bcl-2, BH3 motif, conserved site
Occurring in:
  1. Bcl-2-like protein 1
IPR020731
Domain description: Apoptosis regulator, Bcl-2, BH4 motif, conserved site
Occurring in:
  1. Bcl-2-like protein 1

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