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Structure of E.coli rhomboid protease GlpG in complex with monobactam L62

Source organism: Escherichia coli
Biochemical function: serine-type endopeptidase activity
Biological process: proteolysis
Cellular component: membrane

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EC 3.4.21.105: Rhomboid protease

Reaction catalysed:
Cleaves type-1 transmembrane domains using a catalytic dyad composed of serine and histidine that are contributed by different transmembrane domains.
Systematic name:
-

GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF01694
Domain description: Rhomboid family
Occurring in:
  1. Rhomboid protease GlpG
The deposited structure of PDB entry 3zmh contains 1 copy of Pfam domain PF01694 (Rhomboid family) in Rhomboid protease GlpG. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR035952
Domain description: Rhomboid-like superfamily
Occurring in:
  1. Rhomboid protease GlpG
IPR022764
Domain description: Peptidase S54, rhomboid domain
Occurring in:
  1. Rhomboid protease GlpG
IPR023662
Domain description: Rhomboid protease GlpG
Occurring in:
  1. Rhomboid protease GlpG

Structure domain

CATH CATH domain
1.20.1540.10
Class: Mainly Alpha
Architecture: Up-down Bundle
Topology: Rhomboid-like fold
Homology: Rhomboid-like
Occurring in:
  1. Rhomboid protease GlpG
The deposited structure of PDB entry 3zmh contains 1 copy of CATH domain 1.20.1540.10 (Rhomboid-like fold) in Rhomboid protease GlpG. Showing 1 copy in chain A.

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