4a0i

X-ray diffraction
2.6Å resolution

Crystal structure of Survivin bound to the N-terminal tail of hSgo1

Released:

Function and Biology Details

Biochemical function:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-127464 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Baculoviral IAP repeat-containing protein 5 Chains: A, B
Molecule details ›
Chains: A, B
Length: 142 amino acids
Theoretical weight: 16.41 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: O15392 (Residues: 1-142; Coverage: 100%)
Gene names: API4, BIRC5, IAP4
Sequence domains: Inhibitor of Apoptosis domain
Structure domains: Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A
Shugoshin 1 Chains: C, D
Molecule details ›
Chains: C, D
Length: 5 amino acids
Theoretical weight: 608 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q5FBB7 (Residues: 2-6; Coverage: 1%)
Gene names: SGO1, SGOL1

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: C2
Unit cell:
a: 113.65Å b: 70.514Å c: 82.382Å
α: 90° β: 131.8° γ: 90°
R-values:
R R work R free
0.206 0.204 0.252
Expression system: Not provided