› 4a64

X-ray diffraction
2.57Å resolution

Crystal structure of the N-terminal domain of human Cul4B at 2.57A resolution

Released:
DOI: 10.2210/pdb4a64/pdb
PDB entry 4a64 coloured by chain, front view.
PDB entry 4a64 coloured by chain, side view.
PDB entry 4a64 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Vollmar M, Ayinampudi V, Cooper C, Guo K, Krojer T, Muniz JRC, von Delft F, Weigelt J, Arrowsmith CH, Bountra C, Edwards A, Bullock A

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171786 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cullin-4B Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 354 amino acids
Theoretical weight: 41.95 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q13620 (Residues: 206-557; Coverage: 39%)
Gene names: CUL4B, KIAA0695
Sequence domains: Cullin family
Structure domains: Cullin Repeats

Ligands and Environments

1 bound ligand:
Ligand EDO 7 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: P21
Unit cell:
a: 64.248Å b: 157.091Å c: 92.916Å
α: 90° β: 95.71° γ: 90°
R-values:
R R work R free
0.187 0.184 0.23
Expression system: Escherichia coli BL21(DE3)

Quick links