› 4aqj

X-ray diffraction
1.6Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151915 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein S100-A7 Chain: A
Molecule details ›
Chain: A
Length: 109 amino acids
Theoretical weight: 12.03 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli K-12
UniProt:
  • Canonical: P31151 (Residues: 1-101; Coverage: 100%)
Gene names: PSOR1, S100A7, S100A7C
Sequence domains: S-100/ICaBP type calcium binding domain
Structure domains: EF-hand

Ligands and Environments

3 bound ligands:
Ligand CA 1 x CA
Ligand CL 1 x CL
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: P43212
Unit cell:
a: 51.48Å b: 51.48Å c: 117.23Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.191 0.189 0.225
Expression system: Escherichia coli K-12

Quick links

Citations

3 review citations

Binding of transition metals to S100 proteins.
Gilston et al. (2016)
2 more

1 mention without citation

Structural characterization of S100A15 reveals a novel zinc coordination site among S100 proteins and altered surface chemistry with functional implications for receptor binding.
Murray et al. (2012)