› 4avm

X-ray diffraction
1.91Å resolution

Crystal structure of the N-BAR domain of human bridging integrator 2.

Released:
DOI: 10.2210/pdb4avm/pdb
PDB entry 4avm coloured by chain, front view.
PDB entry 4avm coloured by chain, side view.
PDB entry 4avm coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Allerston CK, Krojer T, Cooper CDO, Vollmar M, Arrowsmith CH, Edwards A, Bountra C, von Delft F, Gileadi O

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193686 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Bridging integrator 2 Chain: A
Molecule details ›
Chain: A
Length: 237 amino acids
Theoretical weight: 28 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9UBW5 (Residues: 11-245; Coverage: 42%)
Gene names: BIN2, BRAP1
Sequence domains: BAR domain
Structure domains: Arfaptin homology (AH) domain/BAR domain

Ligands and Environments

2 bound ligands:
Ligand EDO 3 x EDO
Ligand EPE 2 x EPE
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: C2221
Unit cell:
a: 37.886Å b: 81.248Å c: 150.384Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.165 0.163 0.198
Expression system: Escherichia coli BL21(DE3)

Quick links