› 4b3z

X-ray diffraction
3.05Å resolution

Structure of the human collapsin response mediator protein-1, a lung cancer suppressor

Released:
DOI: 10.2210/pdb4b3z/pdb
PDB entry 4b3z coloured by chain, front view.
PDB entry 4b3z coloured by chain, side view.
PDB entry 4b3z coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure of human collapsin response mediator protein 1: a possible role of its C-terminal tail.
Liu SH, Huang SF, Hsu YL, Pan SH, Chen YJ, Lin YH
Acta Crystallogr F Struct Biol Commun 71 938-45 (2015)
PMID: 26249678

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171961 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Dihydropyrimidinase-related protein 1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 572 amino acids
Theoretical weight: 62.26 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q14194 (Residues: 1-572; Coverage: 100%)
Gene names: CRMP1, DPYSL1, ULIP3
Sequence domains: Amidohydrolase family
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSRRC BEAMLINE BL13B1
Spacegroup: P21
Unit cell:
a: 84.815Å b: 147.846Å c: 86.023Å
α: 90° β: 94.61° γ: 90°
R-values:
R R work R free
0.175 0.174 0.227
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 citation in other articles

A single structurally conserved SUMOylation site in CRMP2 controls NaV1.7 function.
Dustrude et al. (2017)
1 more

4 mentions without citation

Structure of human collapsin response mediator protein 1: a possible role of its C-terminal tail.
Liu et al. (2015)
3 more