› 4bdu

X-ray diffraction
3Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-154513 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Apoptosis regulator BAX; Green fluorescent protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 309 amino acids
Theoretical weight: 34.91 KDa
Source organisms: Expression system: Escherichia coli
UniProt:
  • Canonical: P42212 (Residues: 1-230; Coverage: 97%)
  • Canonical: Q07812 (Residues: 55-128; Coverage: 39%)
Gene names: BAX, BCL2L4, GFP
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
1 modified residue:
Ligand CR2 4 x CR2

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P64
Unit cell:
a: 112.314Å b: 112.314Å c: 293.27Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.216 0.215 0.246
Expression system: Escherichia coli

Quick links

Citations

97 review citations

Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy.
Czabotar et al. (2014)
96 more

22 mentions without citation

Building blocks of the apoptotic pore: how Bax and Bak are activated and oligomerize during apoptosis.
Westphal et al. (2014)
21 more