Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Fibronectin type III
- Ephrin receptor ligand binding domain
- Immunoglobulin-like fold
- Tyrosine-protein kinase, receptor class V, conserved site
- Fibronectin type III superfamily
- Tyrosine-protein kinase ephrin type A/B receptor-like
- Ephrin type-A receptor 4, ligand binding domain
- Galactose-binding-like domain superfamily
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Ephrin type-A receptor 4 (preferred)
PDBe Complex ID:
PDB-CPX-157094 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ephrin type-A receptor 4
Molecule details ›
Chains: A, B
Length: 568 amino acids
Theoretical weight: 62.65 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains:
Length: 568 amino acids
Theoretical weight: 62.65 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
P54764 (Residues: 20-547; Coverage: 55%)
Sequence domains:
- Ephrin receptor ligand binding domain
- Tyrosine-protein kinase ephrin type A/B receptor-like
- Fibronectin type III domain
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
DIAMOND BEAMLINE I24, DIAMOND BEAMLINE I04
Spacegroup:
P3221
Expression system: Homo sapiens
