› 4bkw

X-ray diffraction
2.53Å resolution

Crystal structure of the C-terminal region of human ZFYVE9

Released:
DOI: 10.2210/pdb4bkw/pdb
PDB entry 4bkw coloured by chain, front view.
PDB entry 4bkw coloured by chain, side view.
PDB entry 4bkw coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal Structure of the C-Terminal Region of Human Zfyve9
Williams E
Ph D Thesis (2013)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131922 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Zinc finger FYVE domain-containing protein 9 Chain: A
Molecule details ›
Chain: A
Length: 531 amino acids
Theoretical weight: 59.27 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: O95405 (Residues: 895-1425; Coverage: 37%)
Gene names: MADHIP, SARA, SMADIP, ZFYVE9
Sequence domains: Smad anchor for receptor activation-like, C-terminal
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand EDO 5 x EDO
Ligand PG4 1 x PG4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P6322
Unit cell:
a: 113.751Å b: 113.751Å c: 155.098Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.206 0.204 0.247
Expression system: Escherichia coli BL21

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