4bl8

X-ray diffraction
3.04Å resolution

Crystal structure of full-length human Suppressor of fused (SUFU)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-238711 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Maltose/maltodextrin-binding periplasmic protein; Suppressor of fused homolog Chains: A, B
Molecule details ›
Chains: A, B
Length: 831 amino acids
Theoretical weight: 92.49 KDa
Source organisms: Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P0AEX9 (Residues: 27-393; Coverage: 99%)
  • Canonical: Q9UMX1 (Residues: 32-483; Coverage: 93%)
Gene names: JW3994, SUFU, UNQ650/PRO1280, b4034, malE
Sequence domains:
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: GLC
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: P212121
Unit cell:
a: 97.32Å b: 99.55Å c: 192.94Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.203 0.2 0.246
Expression system: Escherichia coli BL21(DE3)