4bsp

X-ray diffraction
2Å resolution

Crystal structure of R-spondin 1 (Fu1Fu2) - Holmium soak

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-173731 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
R-spondin-1 Chain: A
Molecule details ›
Chain: A
Length: 126 amino acids
Theoretical weight: 13.71 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q2MKA7 (Residues: 31-146; Coverage: 48%)
Gene name: RSPO1
Sequence domains: Furin-like repeat, cysteine-rich
Structure domains: Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A, domain 2

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: I222
Unit cell:
a: 35.63Å b: 64.56Å c: 92.37Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.23 0.228 0.26
Expression system: Homo sapiens