› 4bw7

X-ray diffraction
1.81Å resolution

Calmodulin in complex with strontium

Released:
DOI: 10.2210/pdb4bw7/pdb
PDB entry 4bw7 coloured by chain, front view.
PDB entry 4bw7 coloured by chain, side view.
PDB entry 4bw7 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystallographic snapshots of initial steps in the collapse of the calmodulin central helix.
Kursula P
Acta Crystallogr D Biol Crystallogr 70 24-30 (2014)
PMID: 24419375

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-143908 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calmodulin-1 Chains: A, C
Molecule details ›
Chains: A, C
Length: 149 amino acids
Theoretical weight: 16.85 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P0DP23 (Residues: 1-149; Coverage: 100%)
Gene names: CALM, CALM1, CAM, CAM1
Sequence domains: EF-hand domain pair

Ligands and Environments

1 bound ligand:
Ligand SR 9 x SR
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MAX II BEAMLINE I911-2
Spacegroup: P1
Unit cell:
a: 24.34Å b: 53.94Å c: 59.37Å
α: 88.51° β: 96.61° γ: 93.96°
R-values:
R R work R free
0.208 0.206 0.251
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 review citation

The many structural faces of calmodulin: a multitasking molecular jackknife.
Kursula P. (2014)
4 other articles

2 mentions without citation

Effect of Ca2+ on the promiscuous target-protein binding of calmodulin.
Westerlund et al. (2018)
1 more