› 4bwn

X-ray diffraction
2.27Å resolution

NEMO CC2-LZ DOMAIN

Released:
DOI: 10.2210/pdb4bwn/pdb
PDB entry 4bwn coloured by chain, front view.
PDB entry 4bwn coloured by chain, side view.
PDB entry 4bwn coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Dubosclard V, Duquerroy S, Fontan E, Agou F

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195372 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
NF-kappa-B essential modulator Chains: A, B
Molecule details ›
Chains: A, B
Length: 110 amino acids
Theoretical weight: 12.81 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9Y6K9 (Residues: 258-344; Coverage: 21%)
Gene names: FIP3, IKBKG, NEMO
Sequence domains: Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
Structure domains: Nemo cc2-lz domain - 1d5 darpin complex

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P65
Unit cell:
a: 70.353Å b: 70.353Å c: 78.981Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.216 0.215 0.246
Expression system: Escherichia coli BL21(DE3)

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