› 4cnu

X-ray diffraction
2.8Å resolution

CRYSTAL STRUCTURE OF WT HUMAN CRMP-4 from lattice translocation

Released:
DOI: 10.2210/pdb4cnu/pdb
PDB entry 4cnu coloured by chain, front view.
PDB entry 4cnu coloured by chain, side view.
PDB entry 4cnu coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of human CRMP-4: correction of intensities for lattice-translocation disorder.
Ponnusamy R, Lebedev AA, Pahlow S, Lohkamp B
Acta Crystallogr D Biol Crystallogr 70 1680-94 (2014)
PMID: 24914979

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171963 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Dihydropyrimidinase-related protein 3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 570 amino acids
Theoretical weight: 62.05 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q14195 (Residues: 1-570; Coverage: 100%)
Gene names: CRMP4, DPYSL3, DRP3, ULIP, ULIP1
Sequence domains: Amidohydrolase family
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MAX II BEAMLINE I911-3
Spacegroup: P21212
Unit cell:
a: 96.24Å b: 108.22Å c: 118.19Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.257 0.255 0.295
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

13 citation in other articles

CRMP4 and CRMP2 Interact to Coordinate Cytoskeleton Dynamics, Regulating Growth Cone Development and Axon Elongation.
Tan et al. (2015)
12 more

1 mention without citation

Crystal structure of human CRMP-4: correction of intensities for lattice-translocation disorder.
Ponnusamy et al. (2014)