› 4cpc

X-ray diffraction
2.24Å resolution

Crystal structure of human synaptonemal complex protein SYCP3

Released:
DOI: 10.2210/pdb4cpc/pdb
PDB entry 4cpc coloured by chain, front view.
PDB entry 4cpc coloured by chain, side view.
PDB entry 4cpc coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
A molecular model for the role of SYCP3 in meiotic chromosome organisation.
Syrjänen JL, Pellegrini L, Davies OR
Elife 3 (2014)
PMID: 24950965

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-184975 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Synaptonemal complex protein 3 Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 167 amino acids
Theoretical weight: 19.9 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8IZU3 (Residues: 66-230; Coverage: 70%)
Gene names: SCP3, SYCP3
Sequence domains: Cor1/Xlr/Xmr conserved region

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P1
Unit cell:
a: 49.14Å b: 92.381Å c: 103.367Å
α: 66.53° β: 82.32° γ: 76.53°
R-values:
R R work R free
0.197 0.195 0.226
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

9 review citations

Meiotic Recombination: The Essence of Heredity.
Hunter N. (2015)
8 more

5 mentions without citation

A molecular model for the role of SYCP3 in meiotic chromosome organisation.
Syrjänen et al. (2014)
4 more