4ct7

X-ray diffraction
1.9Å resolution

CNOT9-CNOT1 complex with bound tryptophan

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-107791 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
CCR4-NOT transcription complex subunit 1 Chain: A
Molecule details ›
Chain: A
Length: 243 amino acids
Theoretical weight: 27.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: A5YKK6 (Residues: 1352-1594; Coverage: 10%)
Gene names: AD-005, CDC39, CNOT1, KIAA1007, NOT1
Sequence domains: CCR4-Not complex, Not1 subunit, domain of unknown function DUF3819
CCR4-NOT transcription complex subunit 9 Chain: B
Molecule details ›
Chain: B
Length: 270 amino acids
Theoretical weight: 30.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q92600 (Residues: 16-285; Coverage: 90%)
Gene names: CNOT9, RCD1, RQCD1
Sequence domains: Cell differentiation family, Rcd1-like
Structure domains: Leucine-rich Repeat Variant

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06DA
Spacegroup: C2
Unit cell:
a: 155.031Å b: 66.984Å c: 72.653Å
α: 90° β: 99.85° γ: 90°
R-values:
R R work R free
0.185 0.183 0.221
Expression system: Escherichia coli