4d07

X-ray diffraction
1.85Å resolution

DYNLL2 dynein light chain binds to an extended, unstructured linear motif of myosin 5a tail

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-188500 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Dynein light chain 2, cytoplasmic Chain: A
Molecule details ›
Chain: A
Length: 92 amino acids
Theoretical weight: 10.65 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q96FJ2 (Residues: 1-89; Coverage: 100%)
Gene names: DLC2, DYNLL2
Sequence domains: Dynein light chain type 1
Structure domains: Protein Inhibitor Of Neuronal Nitric Oxide Synthase;
Unconventional myosin-Va Chain: B
Molecule details ›
Chain: B
Length: 27 amino acids
Theoretical weight: 3.02 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q9Y4I1 (Residues: 1275-1297; Coverage: 1%)
Gene names: MYH12, MYO5A

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P6122
Unit cell:
a: 45.16Å b: 45.16Å c: 204.01Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.195 0.193 0.233
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided