› 4dkx

X-ray diffraction
1.9Å resolution

Crystal Structure of the Rab 6A'(Q72L)

Released:
DOI: 10.2210/pdb4dkx/pdb
PDB entry 4dkx coloured by chain, front view.
PDB entry 4dkx coloured by chain, side view.
PDB entry 4dkx coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of Rab6A'(Q72L) mutant reveals unexpected GDP/Mg²⁺ binding with opened GTP-binding domain.
Shin YC, Yoon JH, Jang TH, Kim SY, Heo WD, So I, Jeon JH, Park HH
Biochem Biophys Res Commun 424 269-73 (2012)
PMID: 22750005

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148952 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ras-related protein Rab-6A Chains: A, B
Molecule details ›
Chains: A, B
Length: 216 amino acids
Theoretical weight: 24.63 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P20340 (Residues: 1-208; Coverage: 100%)
Gene names: RAB6, RAB6A
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

2 bound ligands:
Ligand GDP 2 x GDP
Ligand MG 2 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 4A
Unit cell:
a: 36.838Å b: 96.78Å c: 109.997Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.199 0.196 0.25
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Structural basis of membrane trafficking by Rab family small G protein.
Park HH. (2013)
4 other articles

2 mentions without citation

Crystallization reports are the backbone of Acta Cryst. F, but do they have any spine?
Newman et al. (2013)
1 more