› 4e9m

X-ray diffraction
2.15Å resolution

NOD1 card domain with three disulfide-clinched, domain-swapped dimers in the asymmetric unit

Released:
DOI: 10.2210/pdb4e9m/pdb
PDB entry 4e9m coloured by chain, front view.
PDB entry 4e9m coloured by chain, side view.
PDB entry 4e9m coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Berry EA, Huang LS, Walker-Kopp N

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-195094 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleotide-binding oligomerization domain-containing protein 1 Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 144 amino acids
Theoretical weight: 16.69 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q9Y239 (Residues: 2-138; Coverage: 14%)
Gene names: CARD4, NOD1
Sequence domains: Caspase recruitment domain
Structure domains: Death Domain, Fas

Ligands and Environments

1 bound ligand:
Ligand FLC 1 x FLC
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: P212121
Unit cell:
a: 82.846Å b: 85.335Å c: 113.682Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.245 0.245 0.275
Expression system: Escherichia coli BL21

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