4edu

X-ray diffraction
2.58Å resolution

The MBT repeats of human SCML2 in a complex with histone H2A peptide

Released:
Source organism: Homo sapiens

Function and Biology Details

Biochemical function:
  • not assigned
Cellular component:
Sequence domain:

Structure analysis Details

Assemblies composition:
hetero tetramer
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-189721 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Sex comb on midleg-like protein 2 Chain: A
Molecule details ›
Chain: A
Length: 215 amino acids
Theoretical weight: 24.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UQR0 (Residues: 29-243; Coverage: 31%)
Gene name: SCML2
Sequence domains: mbt repeat
Structure domains: SH3 type barrels.
Histone H2A.J Chain: T
Molecule details ›
Chain: T
Length: 16 amino acids
Theoretical weight: 1.86 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q9BTM1 (Residues: 31-46; Coverage: 12%)
Gene names: H2AFJ, H2AJ

Ligands and Environments

No bound ligands
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P43212
Unit cell:
a: 69.949Å b: 69.949Å c: 169.609Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.206 0.204 0.245
Expression systems:
  • Escherichia coli
  • Not provided