› 4ef0

X-ray diffraction
1.5Å resolution

Crystal Structure of the first catalytic domain of protein disulfide isomerase P5

Released:
DOI: 10.2210/pdb4ef0/pdb
PDB entry 4ef0 coloured by chain, front view.
PDB entry 4ef0 coloured by chain, side view.
PDB entry 4ef0 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Vinaik R, Kozlov G, Gehring K

Function and Biology Details

Reaction catalysed: 
Catalyzes the rearrangement of -S-S- bonds in proteins
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-172190 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein disulfide-isomerase A6 Chains: A, B
Molecule details ›
Chains: A, B
Length: 123 amino acids
Theoretical weight: 13.8 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q15084 (Residues: 27-140; Coverage: 27%)
Gene names: ERP5, P5, PDIA6, TXNDC7
Sequence domains: Thioredoxin
Structure domains: Glutaredoxin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: R3
Unit cell:
a: 129.852Å b: 129.852Å c: 45.226Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.177 0.176 0.193
Expression system: Escherichia coli BL21

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