› 4egl

X-ray diffraction
2.9Å resolution

Crystal structure of two tandem RNA recognition motifs of Human antigen R

Released:
DOI: 10.2210/pdb4egl/pdb
PDB entry 4egl coloured by chain, front view.
PDB entry 4egl coloured by chain, side view.
PDB entry 4egl coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Wang H, Zeng F, Liu H, Teng M, Li X

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172379 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ELAV-like protein 1 Chain: A
Molecule details ›
Chain: A
Length: 177 amino acids
Theoretical weight: 19.84 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q15717 (Residues: 18-186; Coverage: 52%)
Gene names: ELAVL1, HUR
Sequence domains: RNA recognition motif
Structure domains: Alpha-Beta Plaits

Ligands and Environments

2 bound ligands:
Ligand SO4 1 x SO4
Ligand GOL 3 x GOL
1 modified residue:
Ligand MLY 1 x MLY

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH3R
Spacegroup: P21212
Unit cell:
a: 41.181Å b: 132.724Å c: 31.102Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.265 0.263 0.294
Expression system: Escherichia coli

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