› 4eje

X-ray diffraction
2.2Å resolution

Structure Of The Tsg101 UEV Domain In Complex With an Ebola PTAP late Domain Peptide

Released:
DOI: 10.2210/pdb4eje/pdb
PDB entry 4eje coloured by chain, front view.
PDB entry 4eje coloured by chain, side view.
PDB entry 4eje coloured by chain, top view.
Source organisms:
Entry author: Camara-Artigas A

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170147 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Tumor susceptibility gene 101 protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 159 amino acids
Theoretical weight: 18.24 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q99816 (Residues: 1-145; Coverage: 37%)
Gene name: TSG101
Sequence domains: UEV domain
Structure domains: Ubiquitin Conjugating Enzyme
Matrix protein VP40 Chains: C, D
Molecule details ›
Chains: C, D
Length: 9 amino acids
Theoretical weight: 1 KDa
Source organism: Ebola virus - Mayinga, Zaire, 1976
Expression system: Not provided
UniProt:
  • Canonical: Q05128 (Residues: 5-13; Coverage: 3%)
Gene name: VP40

Ligands and Environments

1 bound ligand:
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM16
Spacegroup: I4
Unit cell:
a: 105.544Å b: 105.544Å c: 75.304Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.217 0.211 0.274
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided

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