› 4eto

X-ray diffraction
1.54Å resolution

Structure of S100A4 in complex with non-muscle myosin-IIA peptide

Released:
DOI: 10.2210/pdb4eto/pdb
PDB entry 4eto coloured by chain, front view.
PDB entry 4eto coloured by chain, side view.
PDB entry 4eto coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Ramagopal UA, Dulyaninova NG, Kumar PR, Almo SC, Bresnick AR, New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150751 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Protein S100-A4 Chains: A, B
Molecule details ›
Chains: A, B
Length: 93 amino acids
Theoretical weight: 10.76 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P26447 (Residues: 1-93; Coverage: 92%)
Gene names: CAPL, MTS1, S100A4
Sequence domains: S-100/ICaBP type calcium binding domain
Structure domains: EF-hand
Myosin-9 Chain: P
Molecule details ›
Chain: P
Length: 16 amino acids
Theoretical weight: 1.92 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P35579 (Residues: 1908-1923; Coverage: 1%)
Gene name: MYH9

Ligands and Environments

1 bound ligand:
Ligand CA 4 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4A
Spacegroup: P21
Unit cell:
a: 30.279Å b: 91.989Å c: 32.864Å
α: 90° β: 112.6° γ: 90°
R-values:
R R work R free
0.211 0.209 0.251
Expression systems:
  • Escherichia coli
  • Not provided

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