› 4fcx

X-ray diffraction
3Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170814 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Double-strand break repair protein rad32 Chains: A, B
Molecule details ›
Chains: A, B
Length: 404 amino acids
Theoretical weight: 45.66 KDa
Source organism: Schizosaccharomyces pombe 972h-
Expression system: Escherichia coli
UniProt:
  • Canonical: Q09683 (Residues: 15-413; Coverage: 62%)
Gene names: SPAC13C5.07, rad32
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand MN 4 x MN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P212121
Unit cell:
a: 76.408Å b: 82.262Å c: 164.296Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.232 0.227 0.286
Expression system: Escherichia coli

Quick links

Citations

27 review citations

DNA damage sensing by the ATM and ATR kinases.
Maréchal et al. (2013)
26 more

9 mentions without citation

Functional and structural insights into the MRX/MRN complex, a key player in recognition and repair of DNA double-strand breaks.
Tisi et al. (2020)
8 more