› 4fhq

X-ray diffraction
2.25Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-187821 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tumor necrosis factor receptor superfamily member 14 Chain: A
Molecule details ›
Chain: A
Length: 134 amino acids
Theoretical weight: 14.33 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
UniProt:
  • Canonical: Q92956 (Residues: 39-162; Coverage: 51%)
Gene names: HVEA, HVEM, TNFRSF14, UNQ329/PRO509
Sequence domains: TNFR/NGFR cysteine-rich region
Structure domains: Tumor Necrosis Factor Receptor, subunit A, domain 2

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: I422
Unit cell:
a: 94.736Å b: 94.736Å c: 77.159Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.28 0.279 0.292
Expression system: Drosophila melanogaster

Quick links

Citations

1 review citation

Drosophila as a Model for Human Viral Neuroinfections.
Benoit et al. (2022)
3 other articles

5 mentions without citation

Crystal structure of murine 4-1BB and its interaction with 4-1BBL support a role for galectin-9 in 4-1BB signaling.
Bitra et al. (2018)
4 more