› 4fl9

X-ray diffraction
1.9Å resolution

Crystal Structure of bovine hsc70(aa1-554)E213A/D214A at 1.9A Resolution

Released:
DOI: 10.2210/pdb4fl9/pdb
PDB entry 4fl9 coloured by chain, front view.
PDB entry 4fl9 coloured by chain, side view.
PDB entry 4fl9 coloured by chain, top view.
Source organism: Bos taurus
Entry author: Grimm C

Function and Biology Details

Reaction catalysed: 
ATP + H(2)O = ADP + phosphate
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148503 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Heat shock cognate 71 kDa protein Chain: A
Molecule details ›
Chain: A
Length: 554 amino acids
Theoretical weight: 60.98 KDa
Source organism: Bos taurus
Expression system: Escherichia coli
UniProt:
  • Canonical: P19120 (Residues: 1-554; Coverage: 85%)
Gene names: HSC70, HSPA8
Sequence domains: Hsp70 protein
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand TMO 2 x TMO
Ligand DTT 1 x DTT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P21
Unit cell:
a: 66.255Å b: 50.38Å c: 86.638Å
α: 90° β: 99.65° γ: 90°
R-values:
R R work R free
0.194 0.192 0.232
Expression system: Escherichia coli

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