› 4flb

X-ray diffraction
1.8Å resolution

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178430 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Regulation of nuclear pre-mRNA domain-containing protein 2 Chain: A
Molecule details ›
Chain: A
Length: 144 amino acids
Theoretical weight: 16.76 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5VT52 (Residues: 19-149; Coverage: 9%)
Gene names: HSPC099, KIAA0460, RPRD2
Sequence domains: CID domain
Structure domains: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat

Ligands and Environments

3 bound ligands:
Ligand SO4 2 x SO4
Ligand PR 2 x PR
Ligand UNX 5 x UNX
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E
Spacegroup: P43212
Unit cell:
a: 40.339Å b: 40.339Å c: 145.75Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.177 0.175 0.216
Expression system: Escherichia coli

Quick links

Citations

14 review citations

The pol II CTD: new twists in the tail.
Zaborowska et al. (2016)
13 more

5 mentions without citation

What's all the phos about? Insights into the phosphorylation state of the RNA polymerase II C-terminal domain via mass spectrometry.
LeBlanc et al. (2021)
4 more