Function and Biology Details
Reaction catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- DNA-directed DNA polymerase, family B
- DNA polymerase, palm domain superfamily
- DNA polymerase family B, thumb domain
- DNA-directed DNA polymerase, family B, conserved site
- DNA polymerase alpha catalytic subunit, catalytic domain
- DNA/RNA polymerase superfamily
- DNA-directed DNA polymerase, family B, multifunctional domain
- Ribonuclease H superfamily
2 more domains
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
DNA polymerase alpha catalytic subunit A (preferred)
PDBe Complex ID:
PDB-CPX-146554 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA polymerase alpha catalytic subunit A
Molecule details ›
P13382Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ESRF BEAMLINE ID23-1
Spacegroup:
P21
Expression system: Escherichia coli BL21(DE3)
