› 4gli

X-ray diffraction
1.9Å resolution

Crystal Structure of Human SMN YG-Dimer

Released:
DOI: 10.2210/pdb4gli/pdb
PDB entry 4gli coloured by chain, front view.
PDB entry 4gli coloured by chain, side view.
PDB entry 4gli coloured by chain, top view.
Source organisms:
Primary publication:
The survival motor neuron protein forms soluble glycine zipper oligomers.
Martin R, Gupta K, Ninan NS, Perry K, Van Duyne GD
Structure 20 1929-39 (2012)
PMID: 23022347

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-142569 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Maltose/maltodextrin-binding periplasmic protein; Survival motor neuron protein Chain: A
Molecule details ›
Chain: A
Length: 401 amino acids
Theoretical weight: 44.46 KDa
Source organisms: Expression system: Escherichia coli
UniProt:
  • Canonical: P0AEX9 (Residues: 27-395; Coverage: 100%)
  • Canonical: Q16637 (Residues: 263-294; Coverage: 11%)
Gene names: JW3994, SMN, SMN1, SMN2, SMNC, SMNT, b4034, malE
Sequence domains:
Structure domains: Periplasmic binding protein-like II

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: C2
Unit cell:
a: 87.745Å b: 65.914Å c: 84.908Å
α: 90° β: 110.48° γ: 90°
R-values:
R R work R free
0.205 0.203 0.247
Expression system: Escherichia coli

Quick links

Citations

17 review citations

A day in the life of the spliceosome.
Matera et al. (2014)
16 more

8 mentions without citation

Crystal structures of MBP fusion proteins.
Waugh DS. (2016)
7 more