› 4gwu

X-ray diffraction
3Å resolution

Crystal Structure of Fru 2,6-bisphosphate complexes of Porcine Liver Fructose-1,6-bisphosphatase with Filled Central Cavity

Released:
DOI: 10.2210/pdb4gwu/pdb
PDB entry 4gwu coloured by chain, front view.
PDB entry 4gwu coloured by chain, side view.
PDB entry 4gwu coloured by chain, top view.
Source organism: Sus scrofa
Entry authors: Gao Y, Honzatko RB

Function and Biology Details

Reaction catalysed: 
D-fructose 1,6-bisphosphate + H(2)O = D-fructose 6-phosphate + phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132778 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fructose-1,6-bisphosphatase 1 Chain: A
Molecule details ›
Chain: A
Length: 337 amino acids
Theoretical weight: 36.85 KDa
Source organism: Sus scrofa
Expression system: Escherichia coli
UniProt:
  • Canonical: P00636 (Residues: 2-338; Coverage: 100%)
Gene names: FBP, FBP1
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand FDP 1 x FDP
Ligand MG 1 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: I222
Unit cell:
a: 53.999Å b: 81.221Å c: 165.058Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.234 0.231 0.289
Expression system: Escherichia coli

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