› 4gyx

X-ray diffraction
1.49Å resolution

The von Willebrand Factor A3 domain binding region of type III collagen stabilized by the cysteine knot

Released:
DOI: 10.2210/pdb4gyx/pdb
PDB entry 4gyx coloured by chain, front view.
PDB entry 4gyx coloured by chain, side view.
PDB entry 4gyx coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The NC2 domain of type IX collagen determines the chain register of the triple helix.
Boudko SP, Bächinger HP
J Biol Chem 287 44536-45 (2012)
PMID: 23132862

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-135859 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Collagen alpha-1(III) chain Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 31 amino acids
Theoretical weight: 2.88 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P02461 (Residues: 1158-1200; Coverage: 2%)
Gene name: COL3A1
Sequence domains: Collagen triple helix repeat (20 copies)

Ligands and Environments

No bound ligands
1 modified residue:
Ligand HYP 18 x HYP

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 4.2.2
Spacegroup: P21
Unit cell:
a: 19.07Å b: 26.99Å c: 64.12Å
α: 90° β: 92.48° γ: 90°
R-values:
R R work R free
0.18 0.176 0.222
Expression system: Not provided

Quick links

Citations

3 review citations

Pairwise interactions in collagen and the design of heterotrimeric helices.
Jalan et al. (2013)
2 more

5 mentions without citation

Empirical estimation of local dielectric constants: Toward atomistic design of collagen mimetic peptides.
Pike et al. (2015)
4 more