› 4hex

X-ray diffraction
2Å resolution

A novel conformation of calmodulin

Released:
DOI: 10.2210/pdb4hex/pdb
PDB entry 4hex coloured by chain, front view.
PDB entry 4hex coloured by chain, side view.
PDB entry 4hex coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
A novel trans conformation of ligand-free calmodulin.
Kumar V, Chichili VP, Tang X, Sivaraman J
PLoS One 8 e54834 (2013)
PMID: 23382982

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-144015 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calmodulin-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 156 amino acids
Theoretical weight: 17.81 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P0DP26 (Residues: 1-149; Coverage: 100%)
Gene names: Calm, Calm1, Cam, Cam1
Sequence domains: EF-hand domain pair

Ligands and Environments

2 bound ligands:
Ligand ZN 6 x ZN
Ligand CA 4 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X8C
Spacegroup: P21
Unit cell:
a: 38.827Å b: 116.397Å c: 38.797Å
α: 90° β: 94.83° γ: 90°
R-values:
R R work R free
0.211 0.21 0.237
Expression system: Escherichia coli

Quick links

Citations

1 review citation

The many structural faces of calmodulin: a multitasking molecular jackknife.
Kursula P. (2014)
10 other articles

12 mentions without citation

Defining putative glycan cancer biomarkers by MS.
Mechref et al. (2012)
11 more