› 4hfx

X-ray diffraction
2.54Å resolution

Crystal structure of a transcription elongation factor B polypeptide 3 from Homo sapiens, Northeast Structural Genomics consortium target id HR4748B.

Released:
DOI: 10.2210/pdb4hfx/pdb
PDB entry 4hfx coloured by chain, front view.
PDB entry 4hfx coloured by chain, side view.
PDB entry 4hfx coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Seetharaman J, Su M, Ciccosanti C, Sahdev S, Acton TB, Xiao R, Everett JK, Montelione GT, Hunt JF, Tong L, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171978 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Elongin-A Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 97 amino acids
Theoretical weight: 12.14 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q14241 (Residues: 571-656; Coverage: 11%)
Gene names: ELOA, MSTP059, TCEB3
Sequence domains: RNA polymerase II transcription factor SIII (Elongin) subunit A
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces

Ligands and Environments

1 bound ligand:
Ligand SO4 3 x SO4
1 modified residue:
Ligand MSE 12 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4A
Spacegroup: P31
Unit cell:
a: 80.643Å b: 80.643Å c: 63.222Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.236 0.235 0.263

Quick links