PDB 4hon structure summary ‹ Protein Data Bank in Europe (PDBe)

Function and Biology Details

Reaction catalysed:

(1a) a [histone H3]-N(6),N(6),N(6)-trimethyl-L-lysine(9) + 2-oxoglutarate + O(2) = a [histone H3]-N(6),N(6)-dimethyl-L-lysine(9) + succinate + formaldehyde + CO(2)

Biochemical function:

not assigned

Biological process:

not assigned

Cellular component:

not assigned

Sequence domains:

Structure analysis Details

Assembly composition:

hetero dimer (preferred)

Assembly name:

Histone H3.1 and Lysine-specific demethylase 4D (preferred)

PDBe Complex ID:

PDB-CPX-159416 (preferred)

Entry contents:

2 distinct polypeptide molecules

Macromolecules (2 distinct):

Lysine-specific demethylase 4D Chains: A, B

Molecule details ›

Chains: A, B
Length: 330 amino acids
Theoretical weight: 38.14 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:

Canonical: Q6B0I6 (Residues: 12-341; Coverage: 63%)

Gene names: JHDM3D, JMJD2D, KDM4D
Sequence domains:

Structure domains: Cupin

Histone H3.1 Chains: F, G

Molecule details ›

Chains: F, G
Length: 10 amino acids
Theoretical weight: 1.02 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:

Canonical: P68431 (Residues: 7-16; Coverage: 7%)

Gene names: H3C1, H3C10, H3C11, H3C12, H3C2, H3C3, H3C4, H3C6, H3C7, H3C8, H3FA, H3FB, H3FC HIST1H3C, H3FD, H3FF, H3FH, H3FI, H3FJ, H3FK, H3FL, HIST1H3A, HIST1H3B, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J