Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
Interleukin-17 receptor A and Interleukin-17A (preferred)
PDBe Complex ID:
PDB-CPX-172496 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (5 distinct):
Interleukin-17A
Molecule details ›
Chains: A, B, D, E
Length: 122 amino acids
Theoretical weight: 14.12 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: Interleukin-17
Structure domains: Cystine-knot cytokines
Length: 122 amino acids
Theoretical weight: 14.12 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
Q16552 (Residues: 34-155; Coverage: 92%)
Sequence domains: Interleukin-17
Structure domains: Cystine-knot cytokines
Interleukin-17 receptor A
Molecule details ›
Chains: C, F
Length: 301 amino acids
Theoretical weight: 34.86 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains:
Structure domains:
Length: 301 amino acids
Theoretical weight: 34.86 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical: Q96F46 (Residues: 32-317; Coverage: 34%)
Sequence domains:
Structure domains:
Ligands and Environments
1 bound ligand:
No modified residues
Experiments and Validation Details
X-ray source:
APS BEAMLINE 17-ID
Spacegroup:
P3121
Expression systems:
- Homo sapiens
- Spodoptera frugiperda
