› 4i9y

X-ray diffraction
1.75Å resolution

Structure of the C-terminal domain of Nup358

Released:
DOI: 10.2210/pdb4i9y/pdb
PDB entry 4i9y coloured by chain, front view.
PDB entry 4i9y coloured by chain, side view.
PDB entry 4i9y coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural and functional analysis of the C-terminal domain of Nup358/RanBP2.
Lin DH, Zimmermann S, Stuwe T, Stuwe E, Hoelz A
J Mol Biol 425 1318-29 (2013)
PMID: 23353830

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156035 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
E3 SUMO-protein ligase RanBP2 Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 167 amino acids
Theoretical weight: 18.39 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P49792 (Residues: 3062-3224; Coverage: 5%)
Gene names: NUP358, RANBP2
Sequence domains: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
Structure domains: Cyclophilin-like

Ligands and Environments

3 bound ligands:
Ligand GOL 21 x GOL
Ligand CL 6 x CL
Ligand TLA 3 x TLA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL12-2
Spacegroup: P21
Unit cell:
a: 104.062Å b: 97.132Å c: 108.151Å
α: 90° β: 117.38° γ: 90°
R-values:
R R work R free
0.125 0.123 0.158
Expression system: Escherichia coli

Quick links

Citations

18 review citations

Viral and cellular requirements for the nuclear entry of retroviral preintegration nucleoprotein complexes.
Matreyek et al. (2013)
17 more

3 mentions without citation

Structural and functional analysis of the C-terminal domain of Nup358/RanBP2.
Lin et al. (2013)
2 more