› 4ixd

X-ray diffraction
1.8Å resolution

X-ray structure of lfa-1 i-domain in complex with ibe-667 at 1.8a resolution

Released:
DOI: 10.2210/pdb4ixd/pdb
PDB entry 4ixd coloured by chain, front view.
PDB entry 4ixd coloured by chain, side view.
PDB entry 4ixd coloured by chain, top view.
Source organism: Homo sapiens
Entry author: Kallen J

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-149031 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Integrin alpha-L Chain: A
Molecule details ›
Chain: A
Length: 188 amino acids
Theoretical weight: 21.43 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P20701 (Residues: 152-336; Coverage: 16%)
Gene names: CD11A, ITGAL
Sequence domains: von Willebrand factor type A domain
Structure domains: von Willebrand factor, type A domain

Ligands and Environments

2 bound ligands:
Ligand MG 1 x MG
Ligand 1HV 1 x 1HV
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM1A
Spacegroup: I222
Unit cell:
a: 45.3Å b: 65.9Å c: 133.6Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.173 0.172 0.199
Expression system: Escherichia coli BL21

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