Function and Biology Details
Reaction catalysed:
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- Tyrosine-specific protein phosphatase, PTPase domain
- Protein-tyrosine phosphatase-like
- Protein-tyrosine phosphatase, active site
- Tyrosine-specific protein phosphatases domain
- Protein-tyrosine phosphatase, catalytic
- Tyrosine-protein phosphatase non-receptor type 22, catalytic domain
- Tyrosine-protein phosphatase non-receptor type 12/18/22
- Rossmann-like alpha/beta/alpha sandwich fold
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195151 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tyrosine-protein phosphatase non-receptor type 22
Molecule details ›
Chains: A, B
Length: 326 amino acids
Theoretical weight: 38.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Protein-tyrosine phosphatase
Structure domains: Protein tyrosine phosphatase superfamily
Length: 326 amino acids
Theoretical weight: 38.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q9Y2R2 (Residues: 1-303; Coverage: 38%)
Sequence domains: Protein-tyrosine phosphatase
Structure domains: Protein tyrosine phosphatase superfamily
