Function and Biology Details
Reaction catalysed:
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136139 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Tyrosine-protein phosphatase non-receptor type 11
Molecule details ›
Chain: A
Length: 124 amino acids
Theoretical weight: 14.01 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: SH2 domain
Structure domains: SH2 domain
Length: 124 amino acids
Theoretical weight: 14.01 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q06124 (Residues: 97-217; Coverage: 20%)
Sequence domains: SH2 domain
Structure domains: SH2 domain
Ugl-Y3
Molecule details ›
Chain: B
Length: 94 amino acids
Theoretical weight: 10.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Fibronectin type III domain
Structure domains: Immunoglobulins
Length: 94 amino acids
Theoretical weight: 10.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P02751 (Residues: 1538-1582, 1583-1621, 1622-1631; Coverage: 4%)
Sequence domains: Fibronectin type III domain
Structure domains: Immunoglobulins
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
APS BEAMLINE 24-ID-E
Spacegroup:
P61
Expression system: Escherichia coli BL21(DE3)
