› 4jjb

X-ray diffraction
1.65Å resolution

Crystal structure of the Abl-SH3 domain at pH3

Released:
DOI: 10.2210/pdb4jjb/pdb
PDB entry 4jjb coloured by chain, front view.
PDB entry 4jjb coloured by chain, side view.
PDB entry 4jjb coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Camara-Artigas A, Martin-Garcia JM

Function and Biology Details

Reaction catalysed: 
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132602 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tyrosine-protein kinase ABL1 Chain: A
Molecule details ›
Chain: A
Length: 63 amino acids
Theoretical weight: 7.01 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P00519 (Residues: 60-121; Coverage: 6%)
Gene names: ABL, ABL1, JTK7
Sequence domains: SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

2 bound ligands:
Ligand PEG 2 x PEG
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P3212
Unit cell:
a: 50.47Å b: 50.47Å c: 45.12Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.168 0.165 0.225
Expression system: Escherichia coli

Quick links