› 4jnu

X-ray diffraction
1.44Å resolution

Crystal structure of the human Nup57CCS3* coiled-coil segment, space group P21

Released:
DOI: 10.2210/pdb4jnu/pdb
PDB entry 4jnu coloured by chain, front view.
PDB entry 4jnu coloured by chain, side view.
PDB entry 4jnu coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Architecture of the fungal nuclear pore inner ring complex.
Stuwe T, Bley CJ, Thierbach K, Petrovic S, Schilbach S, Mayo DJ, Perriches T, Rundlet EJ, Jeon YE, Collins LN, Huber FM, Lin DH, Paduch M, Koide A, Lu V, Fischer J, Hurt E, Koide S, Kossiakoff AA, Hoelz A
Science 350 56-64 (2015)
PMID: 26316600

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-182247 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleoporin p54 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 40 amino acids
Theoretical weight: 4.73 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q7Z3B4 (Residues: 453-491; Coverage: 8%)
Gene name: NUP54
Sequence domains: Nup54 C-terminal interacting domain
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1
Spacegroup: P21
Unit cell:
a: 39.909Å b: 45.126Å c: 46.384Å
α: 90° β: 113.75° γ: 90°
R-values:
R R work R free
0.186 0.183 0.218
Expression system: Escherichia coli

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Citations

22 review citations

The nuclear pore complex: understanding its function through structural insight.
Beck et al. (2017)
21 more

1 mention without citation

Architecture of the fungal nuclear pore inner ring complex.
Stuwe et al. (2015)